Cerebral Venous Thrombosis after BNT162b2 mRNA SARS-CoV-2 vaccine.

The development of SARS-CoV-2 vaccines has raised several concerns regarding venous thromboembolism, namely cerebral venous thrombosis. Although cerebral venous thrombosis has been reported after administration of a viral vector vaccine, due to a possible auto-immune mechanism inducing thrombocytopenia, the same has not happened in mRNA vaccines. We report two cases of cerebral venous thrombosis, shortly after administration of mRNA vaccine. In both patients, there was no evidence of thrombocytopenia or antiplatelet antibodies, and alternative causes for cerebral venous thrombosis were found. As such, despite the temporal relation of both cases to vaccine administration, these types of cerebral venous thrombosis do not seem to be pathophysiological different from cerebral venous thrombosis not associated to SARS-CoV-2 vaccination. Continuous pharmacovigilance is necessary to monitor possible new events and clarify this association.

Escala pessoal de crenças no mundo justo: adaptação e evidências de validade / Personal belief in a just world scale: adaptation and evidence of validity / Escala personal de creencias en el mundo justo: adaptación y evidencias de validez

As crenças no mundo justo (CMJ) têm permitido a compreensão de uma série de fenômenos sociais, o que tem levado ao desenvolvimento de medidas para sua mensuração. O presente artigo tem como objetivo apresentar evidências de validade de uma versão adaptada da Escala Pessoal de CMJ (CMJ-P). 146 participantes, em sua maioria mulheres (69%), com idades variando de 17 a 66 anos (M = 27,79, DP = 13,67) responderam ao instrumento de CMJ-P, a quatro escalas (CMJ-global, autoestima, bem-estar, religiosidade) para o teste de validade convergente e informaram dados sociodemográficos. Assim como no estudo original, foi encontrada uma solução unifatorial e consistência interna satisfatória (α = 0,83). Adicionalmente, como esperado, foram encontrados relacionamentos positivos da CMJ-P com CMJ-G, autoestima e bem-estar, mas apenas marginalmente significativo com a religiosidade. Verificou-se ainda relação positiva da CMJ-P com a renda e nível de escolaridade. Esta versão adaptada demonstra-se adequada para uso em pesquisas.

Belief in a just world (BJW) has allowed for the comprehension of a series of social phenomena, which has lead to the development of measures for its measurement. The present article has the aim to present evidence of validity for a Portuguese version of Personal BJW Scale (BJW-P). 146 participants, most of them women (69%), with ages varying from 17 to 66 years (M = 27.79, DP = 13.67) answered PBJWP scale, four other scales (BJW-global, self-esteem, well-being, religiosity) for the convergent validity test and informed socio-demographic data. As in the original study, a uni-factorial solution and satisfactory internal consistency (α = 0.83) were found. Additionally, as expected, positive relations were found between PBJW and GBJW, self-esteem, and well-being, but only marginally significant with religiosity. Furthermore, positive relations of PBJW with income, as well as education, were found. The adapted version seems useful for research purposes.

Las creencias en un mundo justo (CMJ) han permitido la comprensión de una serie de fenómenos sociales, que han llevado al desarrollo de medidas para su medición. El presente artículo tiene como objetivo presentar evidencias de validez de una versión adaptada de la Escala Personal de CMJ (CMJ-P). Participaron 146 personas, en su mayoría mujeres (69%), con edades entre 17 a 66 años (M = 27,79, DP = 13,67) que respondieron el instrumento de CMJ-P, a cuatro escalas (CMJ-global, autoestima, bienestar, religiosidad) para el test de validez convergente e informaron datos sociodemográficos. Así como en el estudio original, se encontró una solución unifactorial y consistencia interna satisfactoria (α=0,83). Además, se encontraron relaciones positivas de la CMJ-P con la CMJ-G, autoestima y bienestar, pero sólo marginalmente significativa con la religiosidad. Se encontró también, una relación positiva de la CMJ-P con los ingresos y el nivel de escolaridad. Esta versión adaptada es adecuada para su uso en investigaciones.

Escala Pessoal de Crenças no Mundo Justo: Adaptação e Evidências de Validade / Personal Belief in a Just World Scale: Adaptation and Evidence of Validity / Escala Personal de Creencias en el Mundo Justo: Adaptación y Evidencias de Validez

As crenças no mundo justo (CMJ) têm permitido a compreensão de uma série de fenômenos sociais, o que tem levado ao desenvolvimento de medidas para sua mensuração. O presente artigo tem como objetivo apresentar evidências de validade de uma versão adaptada da Escala Pessoal de CMJ (CMJ-P). 146 participantes, em sua maioria mulheres (69%), com idades variando de 17 a 66 anos (M = 27,79, DP = 13,67) responderam ao instrumento de CMJ-P, a quatro escalas (CMJ-global, autoestima, bem-estar, religiosidade) para o teste de validade convergente e informaram dados sociodemográficos. Assim como no estudo original, foi encontrada uma solução unifatorial e consistência interna satisfatória (α = 0,83). Adicionalmente, como esperado, foram encontrados relacionamentos positivos da CMJ-P com CMJ-G, autoestima e bem-estar, mas apenas marginalmente significativo com a religiosidade. Verificou-se ainda relação positiva da CMJ-P com a renda e nível de escolaridade. Esta versão adaptada demonstra-se adequada para uso em pesquisas.

Belief in a just world (BJW) has allowed for the comprehension of a series of social phenomena, which has lead to the development of measures for its measurement. The present article has the aim to present evidence of validity for a Portuguese version of Personal BJW Scale (BJW-P). 146 participants, most of them women (69%), with ages varying from 17 to 66 years (M = 27.79, DP = 13.67) answered PBJWP scale, four other scales (BJW-global, self-esteem, well-being, religiosity) for the convergent validity test and informed socio-demographic data. As in the original study, a uni-factorial solution and satisfactory internal consistency (α = 0.83) were found. Additionally, as expected, positive relations were found between PBJW and GBJW, self-esteem, and well-being, but only marginally significant with religiosity. Furthermore, positive relations of PBJW with income, as well as education, were found. The adapted version seems useful for research purposes.

Las creencias en un mundo justo (CMJ) han permitido la comprensión de una serie de fenómenos sociales, que han llevado al desarrollo de medidas para su medición. El presente artículo tiene como objetivo presentar evidencias de validez de una versión adaptada de la Escala Personal de CMJ (CMJ-P). Participaron 146 personas, en su mayoría mujeres (69%), con edades entre 17 a 66 años (M = 27,79, DP = 13,67) que respondieron el instrumento de CMJ-P, a cuatro escalas (CMJ-global, autoestima, bienestar, religiosidad) para el test de validez convergente e informaron datos sociodemográficos. Así como en el estudio original, se encontró una solución unifactorial y consistencia interna satisfactoria (α=0,83). Además, se encontraron relaciones positivas de la CMJ-P con la CMJ-G, autoestima y bienestar, pero sólo marginalmente significativa con la religiosidad. Se encontró también, una relación positiva de la CMJ-P con los ingresos y el nivel de escolaridad. Esta versión adaptada es adecuada para su uso en investigaciones.

Considerations on the effects of tidal regimes in the movement of floating litter in an estuarine environment: Case study of the estuarine system of Santos-São Vicente, Brazil.

Floating litter in the estuarine system of Santos-São Vicente is common and is part of day-to-day activities of various users of the area. The objective of the present study was to carry out a quali-quantitative evaluation of the occurrence of floating litter, to infer their sources, and to identify environmental factors that are likely to control occurrence and distribution, with particular emphasis on the effects of tidal regimes. Six sampling stations were selected along the aforementioned estuary and visited monthly between July 2010 and January 2012. Floating litter was counted from a fixed sampling station. Plastics prevailed (89.64%) and their main source was domestic activities (55.41%). More litter was found during ebb spring tides, with higher concentrations obeying confluence patterns of the estuary's channels. Results indicated that occurrence can be attributed to the deficiency in basic sewage system in the area and the deliberate disposal into the estuary by the local population.

Sequential follow-up clinic and ambulatory blood pressure evaluation in a low risk population of white-coat hypertensive patients and in normotensives.

BACKGROUND: In subjects with white-coat hypertension (WCH) it is unclear how ambulatory blood pressure (ABPM) progresses over time and whether they exhibit an increased cardiovascular risk. METHODS: We prospectively evaluated the transition of clinic and ABPM values in 39 clinic and ABPM normotensive subjects (NT) (clinic BP<140/90 mmHg and awake BP<130/85 mmHg, ages 43.4+/-2.6 y) and in 79 untreated subjects (47.2+/-2.4 y) with WCH (clinic BP>140/90, awake ABP<130/85 mmHg) with no other major cardiovascular risk factors. Ambulatory blood pressure was evaluated at baseline and on at least two further occasions during follow-up. RESULTS: At baseline all subjects were untreated and groups did not differ on values of metabolic parameters, BMI, left ventricular mass index, and ABPM values. Subjects were revaluated for ABPM half way through and at the end of follow-up, 35+/-3 and 86+/-4 months in NT and 49+/-4 and 90+/-4 months in WCH. Thirty-six WCH were on antihypertensive treatment (AH) after baseline until the end of follow-up (WCH-tr), whereas 43 WCH (WCH-untr) were free from AH throughout the study. In a similar way all groups showed a significant (p<0.01) progressive increase in 24-h ABPM systolic blood pressure (SBP)/diastolic blood pressure (DBP) from baseline throughout the follow-up in NT (+4.9/2.1+/-0.8/0.9 mmHg), average annual increase of 0.72/0.37 mmHg/y, in WCH-tr (+ 5.0/1.2+/-1.1/1.5 mmHg), average annual increase of 0.66/0.31 mmHg/y and in WCH-untr (+5.4/3.2+/-0.9/1.1 mmHg), average annual increase of 0.74/0.39 mmHg/y. During the follow-up office SBP/DBP (mmHg) significantly rose in NT (+5.7/3.9) but was reduced in WCH-tr (-7.8/5.2) and in WCH-untr (-4.7/1.1). Development of ambulatory hypertension (daytime BP >130 and/or >85 mmHg) occurred in 15.4% (6/39) of NT, in 22.7% (8/36) of WCH-tr and in 26.1% (11/43) of WCH-untr (NS). First cardiovascular events recorded were three in subjects with WCH and none in NT. CONCLUSIONS: After 7.4 years of follow-up, both the progressive increase in ABPM and the rate of transition to ambulatory hypertension in subjects with WCH (either treated or untreated), who were selected under strict criteria were similar to that of normotensive subjects. Also there was no evidence that WCH exhibited a clear higher risk of development cardiovascular events.